Polycystic ovary syndrome (PCOS) also known as polycystic ovaries, Sclerocystic Ovarian Disease, Stein-Leventhal Syndrome, Chronic Anovulatory Syndrome and Polycystic Ovarian Disease (PCOD). It is the most common female endocrine (hormonal) disorder and is characterized by multiple abnormal ovarian cysts.  One of the major biochemical features of polycystic ovary syndrome is insulin resistance accompanied by compensatory hyperinsulinemia (elevated fasting blood insulin levels). There is increasing data that hyperinsulinemia produces the hyperandrogenism of polycystic ovary syndrome by increasing ovarian androgen production, particularly testosterone and by decreasing the serum sex hormone binding globulin concentration. The high levels of androgenic hormones interfere with the pituitary ovarian axis, leading to increased LH levels, anovulation, amenorrhea, miscarriage, and infertility. Hyperinsulinemia has also been associated high blood pressure and increased clot formation and appears to be a major risk factor for the development of heart disease, stroke and type II diabetes。An estimated 5-10% of women of childbearing age are affected by polycystic ovary syndrom and it is one of the leading causes of infertility.

Ovarian drilling, done during laparoscopy, is a procedure in which a laser fibre or electrosurgical needle punctures the ovary 4 to 10 times. This treatment results in a dramatic lowering of male hormones within days and is often performed in women who have polycystic ovary syndrome (PCOS). Studies have shown that up to 80 percent of patients will benefit from such treatment.

Although getting pregnant can be problematical for women with polycystic ovary syndrom, many have found it easier to get pregnant than other infertility, and  ovarian drilling can restore normal ovulation for periods up to six months. 90% will conceive following ovarian drilling although some women may form adhesions following surgery.

Before perform ovarian drilling, physicians will consider this operation after making sure you do not have other condition such as uterus septum, endometrial polyps which may cause miscarriage. 

Symptom of Polycystic ovary syndrome(PCOS):
Amenorrhea (cessation of period) or infrequent periods
Irregular bleeding
Infrequent or no ovulation
Cysts on ovaries
Increased levels of male hormone, like testosterone
Infertility
Chronic pelvic pain for six months or more
Increase in weight or obesity (most women with polycystic ovary syndrom are overweight)
Diabetes; over production and inefficient use of insulin by the body
Lipid abnormalities (high or low cholesterol, high triglycerides)
High blood pressure
Excess facial and body hair growth
 Male-pattern baldness or thinning hair
Acne, oily skin, or dandruff
Dark-colored patches of thick skin on neck, groin, underarms or skin folds
Skin tags in the armpits or neck.

Diagnosis of  Polycystic ovary syndrome(PCOS)

There is little agreement when it comes to how PCOS is diagnosed. Most physicians will consider this diagnosis after making sure you do not have other conditions such as Cushing's disease (overactive adrenal gland), thyroid problems, congenital adrenal hyperplasia or increased prolactin production by the pituitary gland.
Endocrine secretion:TSH, 17-hydroxyprogesterone, prolactin and a dexamethasone suppression test may be advisable.
DHEAS or testosterone help make the diagnosis. A two hour insulin and glucose tolerance test will be obtained. Many physicians tell their patients that insulin values are normal, when in fact the value indicates that insulin may be playing a role in stimulating the development of PCOS. Most labs report levels less than 25-30 miu/ml as normal, while in fact, levels over 10miu/ml on a fasting blood sample suggests that PCOS may be related to hyperinsulinism. As women with polycystic ovary syndrome may be a greater risk for other medical conditions, testing for cardiovascular risk factors such as blood lipids, homocysteine, CRP and PAI-1 (a blood factor that promotes abnormal clotting) will also be carried out.
B Ultrasound
vaginal ultrasound shows enlarged ovaries with an increased number of small (6-10mm) follicles around the periphery (Polycystic Appearing Ovaries or PAO).Most ovarian cysts are harmless, fluid-filled sacs containing immature eggs that attach to the ovaries. But multiple cysts, with a typical appearance of "a string of pearls" or "pearl necklace", are a hallmark of PCOS

Commitment:

In treatment for polycystic ovary syndrom, Antai carried out a policy that if you have not get pregnant within two years after surgery, we would give you a full refund you’ve ever paid.
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Fenglin Chen
Fenglin Chen . graduated from China Medical University with master degree.He has worked in male and female infertility for nearly 30 year, including recurrent miscarriage, uterine fibroid, polycystic ovaries, congenital absence of vagina and uterus.
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