Is it safe for the fetus? Is the question asked by so many women who require vaccination during pregnancy. This is one of this complex issue that needs to be talked through seriously with your doctor, the pros and cons will have to be weighed by you and your partner before making a decision. As a general rule, it is thought that the fetus is more endangered by living vaccines, for example, those against rabies, yellow fever, polio, smallpox, mumps, measles, and German measles, than by inactivated vaccines, such as those for whooping cough, typhoid, cholera, influenza, and polio. Tetanus toxoid vaccine, given as a booster against a possible tetanus risk, is considred safe.