The patient had been married for 5 years when she visited the doctor for RSA. her first and second gestation during 1993-1995 were ended by artificial abortion on the 7th gestation week. she wanted a baby when she was pregnant in 1996 for the third time. however, on the 8th gestation week, the patient had abdominal pain pain and then bled from vagina. Ultrasonic detection showed the termination of the fetal development. then the abortion happened. Thepatient got pregnant twice during 1997-1998. Hematic secretion appeared in vagina on the 7th gestation week of each gestation. traditional Chinese medicament containing gesterol had been used to protect the fetus from abortion and bleeding stopped. On the 10th gestatio week, ultrasonicdetection showed the termination of the fetal development. Drug abortion was performed. The dead fetus was about 7gestation weeks old. Artificial contraception had been carried out since January 1998. The level of antinuclear antibody in periphreral blood of the patient before therapy was determined to be 1:128 according to the method in Example 2.

The pharmaceutical composion of the present invention made from the chromosome of the patient's husband according to example 3 was  subcutaneously injected to the patient for four times on september 6, September 12, September 25 and October 19, 1998 res[ectively. For the first times, the topical reaction strength on the skin after injection was ++++. For the first time, the reaction strength was ++. The patient's level of antinuclear antibody in periphral blood was lowered to 1:64 after the fourth injection.

The patient born  a healthy boy weighed 2800g in september 1999.